CD46 antibody [MEM-258] (FITC)

Catalog number: GTX75834_100tests
Brand: GeneTex
Packing: 100 tests
Price: € 348.00
Expected delivery time: 10 days
GTX75834 FACS Image
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Product specifications for - CD46 antibody [MEM-258] (FITC)

Product group: Antibodies
Category: Primary Antibodies
Subcategory: Fluorescent conjugated
Application: Flow Cytometry
Species: Bovine, Human
Host: Mouse
Target: CD46
Target description: CD46 molecule
Clonality: Monoclonal
Conjugation: FITC
Isotype: IgG1
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Storage instructions: 2-¦C to 8-¦C
Scientific information: 
Scientific info: The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Clone ID: MEM-258
Gene ID: 4179
Swiss prot ID: P15529
Additional information: 
Synonyms: AHUS2; antigen identified by monoclonal antibody TRA-2-10; CD46 antigen, complement regulatory protein; CD46 molecule, complement regulatory protein; complement membrane cofactor protein; MCP; measles virus receptor; membrane cofactor protein; membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen); MIC10; TLX; TRA2.10; trophoblast leucocyte common antigen; trophoblast leukocyte common antigen; trophoblast-lymphocyte cross-reactive antigen