Overview
- SupplierGeneTex
- Product NameCDC6 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.36 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene. van Kempen LC et al., 2016 Dec 14, Sci Transl MedRead more