GTX101226 WB Image
GTX101226 WB Image
CDK2 antibody [N1C3]
GTX101226
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameCDK2 antibody [N1C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Abemaciclib, A Selective CDK4/6 Inhibitor, Restricts the Growth of Pediatric Ependymomas. Liang ML et al., 2020 Dec 1, Cancers (Basel)Read more
- Aqueous extract of Polygonum bistorta modulates proteostasis by ROS-induced ER stress in human hepatoma cells. Liu YH et al., 2017 Jan 30, Sci RepRead more
- Aqueous extracts of Paeonia suffruticosa modulates mitochondrial proteostasis by reactive oxygen species-induced endoplasmic reticulum stress in pancreatic cancer cells. Liu YH et al., 2018 Jul 15, PhytomedicineRead more
- Licochalcone A attenuates glioma cell growth in vitro and in vivo through cell cycle arrest. Lu WJ et al., 2018 Aug 15, Food FunctRead more
- Miconazole induces apoptosis via the death receptor 5-dependent and mitochondrial-mediated pathways in human bladder cancer cells. Yuan SY et al., 2017 Jun, Oncol RepRead more
- RNF4 regulates DNA double-strand break repair in a cell cycle-dependent manner. Kuo CY et al., 2016, Cell CycleRead more
- UBE2M-mediated p27(Kip1) degradation in gemcitabine cytotoxicity. Huang AM et al., 2011 Jul 1, Biochem PharmacolRead more
- Upregulation of LGALS1 is associated with oral cancer metastasis. Li JM et al., 2018, Ther Adv Med OncolRead more