CRK antibody [3H7-E5-H8]

GeneTex

CRK antibody [3H7-E5-H8]

10

Western Blot

Research Use Only

Monoclonal

3H7-E5-H8

Mouse

IgG

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]

Human

2°C to 8°C,-20°C

12352203