CXCR1 antibody, PAb

Biorbyt

CXCR1 antibody, PAb

10

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB:0.1-0.5 μg/ml, IHC-P:0.5-1 μg/ml FC, WB

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to CXCR1. CXCR1 (Chemokine,CXC Motif, Receptor 1), also known as IL8RA or IL8R1, is a chemokine receptor. IL8RA is its human gene. Morris et al. (1992) mapped the IL8RA gene to chromosome 2q35. Hartl et al. (2007) concluded that CXCR1 cleavage and its functional consequences represent an important pathophysiologic mechanism in CF and other neutrophilic airway diseases. Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Human

2°C to 8°C,-20°C

12352203