Desmin antibody, MAb

Biorbyt

Desmin antibody, MAb

10

Western Blot, ImmunoHistoChemistry

Western blot - 2 μg/ml - Human, mouse, rat, rabbit - - - Immunohistochemistry(Paraffin-embedded Section) - 2-4 μg/ml - Human, mouse, rat, rabbit - - - By Heat WB, IHC

Research Use Only

Monoclonal

Clone: DE-U-10

100 ug/ml

Mouse

IgG1

Mouse monoclonal antibody to Desmin belongs to the type III family of intermediate filaments, a class of cytoskeletal elements. DES gene encodes desmin, a muscle-specific cytoskeletal protein found in smooth, cardiac, and heart muscles. Tidball 1992 found that desmin was codistributed with actin thin filaments within the cellular processes of myotendinous junctions in frog skeletal muscle. DES gene contains 9 exons and spans about 8.4 kb. By in situ hybridization, Viegas-Pequignot et al. 1989 localized the gene to 2q35. Desmin mutation responsible for idiopathic dilated cardiomyopathy.

Human, Mouse, Rabbit, Rat

2°C to 8°C,-20°C

12352203