Overview
- SupplierGeneTex
- Product NameDNA-PKcs antibody [C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThe PRKDC gene encodes the catalytic subunit of a nuclear DNA-dependent serine/threonine protein kinase (DNA-PK). The second component is the autoimmune antigen Ku (MIM 152690), which is encoded by the G22P1 gene on chromosome 22q. On its own, the catalytic subunit of DNA-PK is inactive and relies on the G22P1 component to direct it to the DNA and trigger its kinase activity; PRKDC must be bound to DNA to express its catalytic properties.[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Computational inference of cancer-specific vulnerabilities in clinical samples. Jang K et al., 2020 Jun 29, Genome BiolRead more