DUX4 Antibody (OASE00138)

Aviva Systems Biology

DUX4 Antibody (OASE00138)

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Research Use Only

Monoclonal

P2B1

1 mg/ml

Unconjugated

DUX4L1

double homeobox 4 like 1 (pseudogene)

double homeobox protein 10; double homeobox protein 4/10; DUX10; DUX4

Mouse

IgG1

DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).

Human, Mouse

-20°C

12352203