EED antibody
GTX14294
Overview
- SupplierGeneTex
- Product NameEED antibody
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- HostChicken
- IsotypeIgY
- Scientific DescriptionThis gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Four transcript variants encoding distinct isoforms have been identified for this gene. The four isoforms are differentialy expressed during ES cell differentiation, with four isoforms intially expressed. Only isoform 3 then remains after differentiation.
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors. Patel AJ et al., 2019 Oct 22, Proc Natl Acad Sci U S ARead more