eIF2 alpha antibody
GTX112919
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameeIF2 alpha antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.4 mg/ml
- IsotypeIgG
- Scientific DescriptionThe translation initiation factor eIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (36 kD), beta (38 kD, MIM 603908), and gamma (52 kD, MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of eIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 6-Shogaol induces cell cycle arrest and apoptosis in human hepatoma cells through pleiotropic mechanisms. Wu JJ et al., 2015 Sep 5, Eur J PharmacolRead more
- Arsenic trioxide induces unfolded protein response in vascular endothelial cells. Weng CY et al., 2014 Feb, Arch ToxicolRead more
- Luteolin modulates 6-hydroxydopamine-induced transcriptional changes of stress response pathways in PC12 cells. Hu LW et al., 2014, PLoS OneRead more