EP300 (phospho Ser1834) antibody

GeneTex

EP300 (phospho Ser1834) antibody

10

Western Blot

Research Use Only

Polyclonal

Rabbit

IgG

Phosphorylated

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C,-20°C

12352203