ESRP1 antibody [27H12]

GeneTex

ESRP1 antibody [27H12]

10

Western Blot, ELISA

Research Use Only

Monoclonal

27H12

1 mg/ml

Mouse

IgG

Epithelial splicing regulatory protein 1 (Esrp-1) is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2, and also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). EsrpP-1 acts by directly binding specific sequences in mRNAs. It binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.

Mouse

2°C to 8°C,-20°C

12352203