GTX100260 IP Image
GTX100260 IP Image
FACL4 antibody [C3], C-term
GTX100260
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameFACL4 antibody [C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.44 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases. Ndiaye H et al., 2020 Apr 30, Biosci RepRead more
- Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling. Filadi R et al., 2015 Apr 28, Proc Natl Acad Sci U S ARead more
- Relieving ferroptosis may partially reverse neurodegeneration of the auditory cortex. Chen X et al., 2020 Nov, FEBS JRead more
- Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Garcia-Bermudez J et al., 2019 Mar, NatureRead more
- The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells. Radif Y et al., 2018 Nov, Mol Cell BiochemRead more