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ProductsBack/Filaggrin antibody [SPM181]
GTX34732 IHC-P Image
GTX34732 IHC-P Image
GTX34732 IHC-P Image

Filaggrin antibody [SPM181]

Research Use Only
GTX34732
GeneTex
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
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Overview

  • Supplier
    GeneTex
  • Product Name
    Filaggrin antibody [SPM181]
  • Delivery Days Customer
    10
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    SPM181
  • Concentration
    0.2 mg/ml
  • Host
    Mouse
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Expression of caspase 14 and filaggrin in oral squamous carcinoma. Scharenberg C et al., 2013 Dec, Head Neck Pathol
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