GTX101178 IHC-P Image
GTX101178 IHC-P Image
Galactosidase alpha antibody [N1C2]
GTX101178
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameGalactosidase alpha antibody [N1C2]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.157 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Rapid Clathrin-Mediated Uptake of Recombinant alpha-Gal-A to Lysosome Activates Autophagy. Ivanova MM et al., 2020 May 30, BiomoleculesRead more
- The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinsons disease brain in association with the pathologic accumulation of alpha-synuclein. Nelson MP et al., 2018 Feb, Neurobiol DisRead more