GTX107748 WB Image
GTX107748 WB Image
GPR30 antibody [C2C3], C-term
GTX107748
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameGPR30 antibody [C2C3], C-term
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.55 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Estradiol and tamoxifen induce cell migration through GPR30 and activation of focal adhesion kinase (FAK) in endometrial cancers with low or without nuclear estrogen receptor alpha (ERalpha). Tsai CL et al., 2013, PLoS OneRead more
- Estradiol rapidly modulates odor responses in mouse vomeronasal sensory neurons. Cherian S et al., 2014 Jun 6, NeuroscienceRead more
- Estrogen receptor signaling in the ferutinin-induced osteoblastic differentiation of human amniotic fluid stem cells. Zavatti M et al., 2016 Nov 1, Life SciRead more