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GTX106109 ICC/IF Image
GTX106109 ICC/IF Image
GTX106109 ICC/IF Image

GSTZ1 antibody [N1C3]

Research Use Only
GTX106109
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    GSTZ1 antibody [N1C3]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.98 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Thus defects in this enzyme may lead to severe metabolic disorders including alkaptonuria, phenylketonuria and tyrosinaemia. Several transcript variants of this gene encode multiple protein isoforms. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • GSTZ1 deficiency promotes hepatocellular carcinoma proliferation via activation of the KEAP1/NRF2 pathway. Li J et al., 2019 Oct 30, J Exp Clin Cancer Res
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  • GSTZ1-1 downregulates Wnt/beta-catenin signalling in hepatocellular carcinoma cells. Lei C et al., 2020 Jan, FEBS Open Bio
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