Hepatitis B Virus Surface Antigen antibody (Biotin)

Catalog number: GTX41173_100ul
Brand: GeneTex
Packing: 100 ul
Price: € 309.00
Expected delivery time: 10 days
Quantity:

Product specifications for - Hepatitis B Virus Surface Antigen antibody (Biotin)

Overview: 
Product group: Antibodies
Category: Primary Antibodies
Subcategory: Other
Application: ELISA
Species: Virus
Host: Rabbit
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Properties: 
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Concentration: 4 mg/ml
Storage instructions: 2°C to 8°C, -20°C or -80°C
Scientific information: 
Scientific info: Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.