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Hephaestin antibody [N1N2], N-term

Research Use Only
GTX115300
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Hephaestin antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.32 mg/ml
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes. Ranganathan PN et al., 2012 Feb 28, Proc Natl Acad Sci U S A
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  • Immunoreactive hephaestin and ferroxidase activity are present in the cytosolic fraction of rat enterocytes. Ranganathan PN et al., 2012 Aug, Biometals
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  • Iron Together with Lipid Downregulates Protein Levels of Ceruloplasmin in Macrophages Associated with Rapid Foam Cell Formation. Wang Q et al., 2016 Oct 1, J Atheroscler Thromb
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