Hsp47 antibody, MAb (APC)
ORB148126
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
Overview
- SupplierBiorbyt
- Product NameHsp47 antibody, MAb (APC)
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- Applications SupplierWB (1:1000), ICC/IF (1:100) ICC, WB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1C4-1A6
- Concentration1 mg/ml
- ConjugateAPC
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMouse monoclonal to Hsp47 (APC). Hsp47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of Hsp47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since Hsp47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils..
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203