IGF1R antibody [AMY10-105.8 (1H7)] (Low endotoxin, azide free)

GeneTex

IGF1R antibody [AMY10-105.8 (1H7)] (Low endotoxin, azide free)

10

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking

Research Use Only

Monoclonal

AMY10-105.8 (1H7)

1 mg/ml

Mouse

IgG

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Human

2°C to 8°C,-20°C

12352203