GTX102731 IHC-P Image
GTX102731 IHC-P Image
IL10 Receptor alpha antibody
GTX102731
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameIL10 Receptor alpha antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.85 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A Fucoxanthinol Induces Apoptosis in a Pancreatic Intraepithelial Neoplasia Cell. Terasaki M et al., 2021 Mar-Apr, Cancer Genomics ProteomicsRead more
- IL10 inhibits starvation-induced autophagy in hypertrophic scar fibroblasts via cross talk between the IL10-IL10R-STAT3 and IL10-AKT-mTOR pathways. Shi J et al., 2016 Mar 10, Cell Death DisRead more