KDEL antibody, PAb (ATTO-488)

Biorbyt

KDEL antibody, PAb (ATTO-488)

10

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000), ICC/IF (1:100) ICC, WB, IHC

Research Use Only

Polyclonal

1 mg/ml

Atto 488

Rabbit

Rabbit polyclonal to KDEL (ATTO-488). The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu). Grp78 and Grp94 and PDI all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER..

Human, Mouse, Rat

2°C to 8°C

12352203