LEF1 antibody [1C3]

GeneTex

LEF1 antibody [1C3]

10

Western Blot

Research Use Only

Monoclonal

1C3

~1 mg/ml

Mouse

IgG

Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.

Human

2°C to 8°C,-20°C

12352203