hCG Receptor / LH Receptor Antibody
ORB386094
Overview
- SupplierBiorbyt
- Product NamehCG Receptor / LH Receptor Antibody
- Delivery Days Customer16
- ApplicationsELISA
- Applications SupplierELISA (order BSA/sodium azide-free format for coating),Flow cytometry: 1-2ug/million cells,Western blot: 0.5-1ug/ml ELISA, FACS, WB
- CertificationResearch Use Only
- Clone IDLHCGR/1417
- IsotypeIgG
- Scientific DescriptionRecognizes a protein of 78-85 kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin (LHR/CGR). Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
- UNSPSC12352203