LIFR antibody [9B23]
GTX52910
Overview
- SupplierGeneTex
- Product NameLIFR antibody [9B23]
- Delivery Days Customer10
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID9B23
- Concentration500 ug/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2018]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203