Overview
- SupplierGeneTex
- Product NameMAP4K4 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.19 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Definition of PKC-alpha, CDK6, and MET as therapeutic targets in triple-negative breast cancer. Hsu YH et al., 2014 Sep 1, Cancer ResRead more