MMP9 Antibody / Matrix metalloproteinase-9
ORB534057
Overview
- SupplierBiorbyt
- Product NameMMP9 Antibody / Matrix metalloproteinase-9
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1) IHC-P
- CertificationResearch Use Only
- Clone IDMXMP9-1R
- IsotypeIgG
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens and other extracellular matrix proteins. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [Wiki]
- UNSPSC12352203