MIA3 antibody [N1], N-term

GeneTex

MIA3 antibody [N1], N-term

9

Research Use Only

0.30 mg/ml

IgG

Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.

2°C to 8°C,-20°C

12352203