GTX113776 WB Image
GTX113776 WB Image
MITF antibody [N2C1], Internal
GTX113776
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameMITF antibody [N2C1], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Androgen receptor promotes melanoma metastasis via altering the miRNA-539-3p/USP13/MITF/AXL signals. Wang Y et al., 2017 Mar 23, OncogeneRead more
- Critical role of glioma-associated oncogene homolog 1 in maintaining invasive and mesenchymal-like properties of melanoma cells. Gunarta IK et al., 2017 Aug, Cancer SciRead more
- PI3K signalling is required for a TGFbeta-induced epithelial-mesenchymal-like transition (EMT-like) in human melanoma cells. Schlegel NC et al., 2015 Jan, Exp DermatolRead more