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GTX112027 WB Image
GTX112027 WB Image
GTX112027 WB Image

NEK8 antibody [N1N2], N-term

Research Use Only
GTX112027
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    NEK8 antibody [N1N2], N-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Mutations in NEK8 link multiple organ dysplasia with altered Hippo signalling and increased c-MYC expression. Frank V et al., 2013 Jun 1, Hum Mol Genet
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  • The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ. Habbig S et al., 2012 Dec 15, Hum Mol Genet
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