Overview
- SupplierGeneTex
- Product NameNOX1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1.03 mg/ml
- IsotypeIgG
- Scientific DescriptionVoltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 15-Deoxy-delta12,14-PGJ 2, by activating peroxisome proliferator-activated receptor-gamma, suppresses p22phox transcription to protect brain endothelial cells against hypoxia-induced apoptosis. Wu JS et al., 2014 Aug, Mol NeurobiolRead more
- Apocynin Prevents Abnormal Megakaryopoiesis and Platelet Activation Induced by Chronic Stress. Sandrini L et al., 2017, Oxid Med Cell LongevRead more
- Essential Role of NADPH Oxidase-Dependent Production of Reactive Oxygen Species in Maintenance of Sustained B Cell Receptor Signaling and B Cell Proliferation. Feng YY et al., 2019 May 1, J ImmunolRead more
- Gallic Acid Reduces Blood Pressure and Attenuates Oxidative Stress and Cardiac Hypertrophy in Spontaneously Hypertensive Rats. Jin L et al., 2017 Nov 15, Sci RepRead more
- Increasing muscle mass improves vascular function in obese (db/db) mice. Qiu S et al., 2014 Jun 25, J Am Heart AssocRead more
- Interphotoreceptor Retinoid-Binding Protein Mitigates Cellular Oxidative Stress and Mitochondrial Dysfunction Induced by All-trans-Retinal. Lee M et al., 2016 Apr, Invest Ophthalmol Vis SciRead more
- KRIT1 loss-mediated upregulation of NOX1 in stromal cells promotes paracrine pro-angiogenic responses. Finetti F et al., 2020 Apr, Cell SignalRead more
- Long-term methylglyoxal treatment impairs smooth muscle contractility in organ-cultured rat mesenteric artery. Mukohda M et al., 2012 Jan, Pharmacol ResRead more
- NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. Liang S et al., 2019 Mar, GastroenterologyRead more
- Neuronal NAD(P)H oxidases contribute to ROS production and mediate RGC death after ischemia. Dvoriantchikova G et al., 2012 May 14, Invest Ophthalmol Vis SciRead more