NOX5 antibody, PAb

Biorbyt

NOX5 antibody, PAb

16

Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Western blot - 0.1-0.5 μg/ml - Human - - - Immunohistochemistry(Paraffin-embedded Section) - 0.5-1 μg/ml - Human - - - By Heat Immunocytochemistry - 0.5-1 μg/ml - Human - - - ICC, WB, IHC

Research Use Only

Polyclonal

500 ug/ml

Rabbit

IgG

Rabbit Polyclonal to NOX5. NOX5(Nadph Oxidase 5), also known as NOX5A or NOX5B, is a protein which in humans is encoded by the NOX5 gene. The International Radiation Hybrid Mapping Consortium mapped the NOX5 gene to chromosome 15. NOX5 is a novel NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca2+-dependent manner. Banfi et al. (2001) found that, when heterologously expressed, NOX5 was quiescent in unstimulated cells. However, in response to elevations of the cytosolic Ca2+ concentration, it generated large amounts of superoxide. Using RT-PCR and Southern and Western blot analyses, Kamiguti et al. (2005) identified NOX5 as a flavin-containing Ca2+-dependent oxidase present in hairy leukemic cells (HC), but not normal B cells.

Human

2°C to 8°C,-20°C

12352203