Overview
- SupplierGeneTex
- Product NameNRF1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 1,25-Dihydroxyvitamin D3 modulates the effects of sublethal BPA on mitochondrial function via activating PI3K-Akt pathway and 17beta-estradiol secretion in rat granulosa cells. Lee CT et al., 2019 Jan, J Steroid Biochem Mol BiolRead more
- A mitohormetic response to pro-oxidant exposure in the house mouse. Zhang Y et al., 2018 Jan 1, Am J Physiol Regul Integr Comp PhysiolRead more
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol RepRead more
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol RepRead more
- Caveolin-1 Expression Ameliorates Nephrotic Damage in a Rabbit Model of Cholesterol-Induced Hypercholesterolemia. Chen YH et al., 2016, PLoS OneRead more
- Caveolin-1 provides palliation for adverse hepatic reactions in hypercholesterolemic rabbits. Chen YH et al., 2014, PLoS OneRead more
- Physiological cyclic strain promotes endothelial cell survival via the induction of heme oxygenase-1. Liu XM et al., 2013 Jun 15, Am J Physiol Heart Circ PhysiolRead more
- Rosiglitazone activation of PPARgamma-dependent signaling is neuroprotective in mutant huntingtin expressing cells. Chiang MC et al., 2015 Nov 1, Exp Cell ResRead more
- The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression. Ma B et al., 2019 Mar 4, Nat CommunRead more