Overview
- SupplierGeneTex
- Product NamePAK1 antibody [N2C2], Internal
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.84 mg/ml
- IsotypeIgG
- Scientific DescriptionPAK proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. These proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 regulates cell motility and morphology. Alternativelt spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via beta-catenin-mediated stemness. Chen MJ et al., 2016 Oct 7, Sci RepRead more