Paxillin antibody, MAb

Biorbyt

Paxillin antibody, MAb

10

Western Blot, ImmunoCytoChemistry

Western blot - 1-2 μg/ml - Human, mouse, rat, chicken - - - Immunocytochemistry - 1 μg/ml - Human, mouse, rat, chicken - - - ICC, WB

Research Use Only

Monoclonal

Clone: PXC-10

100 ug/ml

Mouse

IgG1

Mouse Monoclonal to Paxillin. The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.

Canine, Chicken, Equine, Human, Mouse, Rabbit, Rat

2°C to 8°C,-20°C

12352203