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GTX118886 ICC/IF Image
GTX118886 ICC/IF Image
GTX118886 ICC/IF Image

PDE10A antibody [C2C3], C-term

Research Use Only
GTX118886
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    PDE10A antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    3.1 mg/ml
  • Isotype
    IgG
  • Scientific Description
    Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).[supplied by OMIM]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer. Fusco JP et al., 2018 May 15, Cancer Med
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  • Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and beta-catenin-dependent TCF transcriptional activity. Li N et al., 2015 Mar 19, Oncogene
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  • Suppression of beta-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10. Li N et al., 2015 Sep 29, Oncotarget
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