GTX37356 WB Image
GTX37356 WB Image
PGC1 alpha antibody
GTX37356
Overview
- SupplierGeneTex
- Product NamePGC1 alpha antibody
- Delivery Days Customer10
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5 mg/ml
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- A mitohormetic response to pro-oxidant exposure in the house mouse. Zhang Y et al., 2018 Jan 1, Am J Physiol Regul Integr Comp PhysiolRead more
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol RepRead more
- Acute and chronic effects of resistance training on skeletal muscle markers of mitochondrial remodeling in older adults. Mesquita PHC et al., 2020 Aug, Physiol RepRead more
- Bovine Milk Extracellular Vesicles (EVs) Modification Elicits Skeletal Muscle Growth in Rats. Parry HA et al., 2019, Front PhysiolRead more
- Changes in Metabolism, Mitochondrial Function, and Oxidative Stress Between Female Rats Under Nonreproductive and 3 Reproductive Conditions. Hyatt HW et al., 2019 Jan, Reprod SciRead more
- Coordinated regulation of hepatic FoxO1, PGC-1alpha and SREBP-1c facilitates insulin action and resistance. Sajan MP et al., 2018 Mar, Cell SignalRead more
- CTRP9 induces mitochondrial biogenesis and protects high glucose-induced endothelial oxidative damage via AdipoR1 -SIRT1- PGC-1alpha activation. Cheng L et al., 2016 Sep 2, Biochem Biophys Res CommunRead more
- Divergent skeletal muscle mitochondrial phenotype between male and female patients with chronic heart failure. Garnham JO et al., 2020 Feb, J Cachexia Sarcopenia MuscleRead more
- Effects of a Bacterial Infection on Mitochondrial Function and Oxidative Stress in a Songbird. Zhang Y et al., 2021 Mar-Apr, Physiol Biochem ZoolRead more
- High activity before breeding improves reproductive performance by enhancing mitochondrial function and biogenesis. Zhang Y et al., 2018 Apr 6, J Exp BiolRead more