Bio-Connect

PIAS3 antibody, PAb

Research Use Only
ORB66717
Biorbyt
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Biorbyt
  • Product Name
    PIAS3 antibody, PAb
  • Delivery Days Customer
    16
  • Applications
    Western Blot
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Rabbit polyclonal to PIAS3.Protein inhibitor of activated STAT3 (PIAS3) is a member of the PIAS proteins. The mammalian PIASfamily is composed of four proteins: PIAS1, PIAS2 (PIASx), PIAS3, and PIAS4 (PIASy). PIAS proteinsfunction as E3 small ubiquitin-like modifier (SUMO) ligases, which facilitate the conjugation of SUMOto the specific protein substrates. PIAS3 has been shown to play important roles in the transcriptionalregulation of various cellular pathways, including STAT, SMAD and the steroid hormone signalingpathways. The effects of this transcriptional co-regulation, transactivation or silencing, may varydepending upon the biological context.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203