PLA2R1 Antibody, Rabbit PAb

Catalog number: HPA012657
Brand: Atlas Antibodies
Packing: 100 ul
Price: € 327.00
Expected delivery time: 7 days

Product specifications for - PLA2R1 Antibody, Rabbit PAb

Product group: Antibodies
Category: Primary Antibodies
Application: ImmunoFluorescence, ImmunoHistoChemistry
Host: Rabbit
Target: PLA2R1
Target description: phospholipase A2 receptor 1, 180kDa
Clonality: Polyclonal
Isotype: IgG
Purity: Purification method: Affinity purified using the PrEST antigen as affinity ligand
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352203
Form supplied: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage instructions: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Scientific information: 
Scientific info: Specification: This antibody has been used for staining of 48 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 patients for each cancer type.
Gene ID: 22925
Swiss prot ID: Q13018
Related products: 
Related products: Corresponding Atlas Antigen: APrEST72110
Additional information: 
Synonyms: HPA012657; PLA2R / PLA2R1; PLA2R1; PLA2R; PLA2IR; PLA2G1R; PLA2-R; CLEC13C; secretory phospholipase A2 receptor; M-type receptor; C-type lectin domain family 13 member C; 180 kDa secretory phospholipase A2 receptor; phospholipase A2 receptor 1, 180kDa
Debiec H, Ronco P. "PLA2R autoantibodies and PLA2R glomerular deposits in membranous nephropathy.". N Engl J Med 2011 Feb 17; 364(7):689-90. DOI: 10.1056/NEJMc1011678. Read more
Debiec H, Martin L, Jouanneau C, Dautin G, Mesnard L, Rondeau E, Mousson C, Ronco P. "Autoantibodies specific for the phospholipase A2 receptor in recurrent and De Novo membranous nephropathy.". Am J Transplant 2011 Oct; 11(10):2144-52. Epub 2011 Aug 9. DOI: 10.1111/j.1600-6143.2011.03643.x. Read more
Hoxha E, Kneißler U, Stege G, Zahner G, Thiele I, Panzer U, Harendza S, Helmchen UM, Stahl RA. "Enhanced expression of the M-type phospholipase A2 receptor in glomeruli correlates with serum receptor antibodies in primary membranous nephropathy.". Kidney Int 2012 Oct; 82(7):797-804. Epub 2012 Jun 6. DOI: 10.1038/ki.2012.209. Read more
Svobodova B, Honsova E, Ronco P, Tesar V, Debiec H. "Kidney biopsy is a sensitive tool for retrospective diagnosis of PLA2R-related membranous nephropathy.". Nephrol Dial Transplant 2013 Jul; 28(7):1839-44. Epub 2012 Dec 6. DOI: 10.1093/ndt/gfs439. Read more
Augert A, Vindrieux D, Girard CA, Le Calvé B, Gras B, Ferrand M, Bouchet BP, Puisieux A, de Launoit Y, Simonnet H, Lambeau G, Bernard D. "PLA2R1 kills cancer cells by inducing mitochondrial stress.". Free Radic Biol Med 2013 Dec; 65:969-77. Epub 2013 Aug 29. DOI: 10.1016/j.freeradbiomed.2013.08.177. Read more
A Griveau, G Devailly, L Eberst, N Navaratnam, B Le Calvé, M Ferrand, P Faull, A Augert, R Dante, J M Vanacker, D Vindrieux, D Bernard. "The PLA2R1-JAK2 pathway upregulates ERRα and its mitochondrial program to exert tumor-suppressive action". Oncogene April 04, 2016. DOI: 10.1038/onc.2016.43. Read more