GTX27335 WB Image
Plasminogen antibody (Biotin)
GTX27335
Overview
- SupplierGeneTex
- Product NamePlasminogen antibody (Biotin)
- Delivery Days Customer10
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- HostGoat
- IsotypeIgG
- Scientific DescriptionPlasminogen is a plasma protein synthesised mostly in the liver. Plasma concentration is usually in the range of 70 - 200mg/L. Plasminogen is activated by tissue-plasminogen activator, urokinase and streptokinase, to form plasmin. Activation results from the cleavage and release of the preactivation peptide. Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203