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GTX102206 ICC/IF Image
GTX102206 ICC/IF Image
GTX102206 ICC/IF Image

PPP2R1A antibody

Research Use Only
GTX102206
GeneTex
Product group Antibodies
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    PPP2R1A antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.12 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Tsao HW et al., 2013 Sep 24, Proc Natl Acad Sci U S A
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  • Neuronal ceroid lipofuscinosis related ER membrane protein CLN8 regulates PP2A activity and ceramide levels. Adhikari B et al., 2019 Feb 1, Biochim Biophys Acta Mol Basis Dis
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  • PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo. Yen YT et al., 2019 Dec 30, Cells
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  • PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Yen YT et al., 2021 Jun 2, Commun Biol
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  • PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Yen YT et al., 2021 Jun 2, Commun Biol
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  • Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress. Martina JA et al., 2018 Aug 10, J Biol Chem
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  • The Royal Australasian College of Physicians Golden Jubilee meeting. Sydney, 8-13 May 1988. Proceedings of meetings of special societies and colleges. Abstracts., 1988 May, Aust N Z J Med
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