Overview
- SupplierGeneTex
- Product NamePPP2R1A antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.12 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter. Tsao HW et al., 2013 Sep 24, Proc Natl Acad Sci U S ARead more
- Neuronal ceroid lipofuscinosis related ER membrane protein CLN8 regulates PP2A activity and ceramide levels. Adhikari B et al., 2019 Feb 1, Biochim Biophys Acta Mol Basis DisRead more
- PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo. Yen YT et al., 2019 Dec 30, CellsRead more
- PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Yen YT et al., 2021 Jun 2, Commun BiolRead more
- PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Yen YT et al., 2021 Jun 2, Commun BiolRead more
- Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress. Martina JA et al., 2018 Aug 10, J Biol ChemRead more
- The Royal Australasian College of Physicians Golden Jubilee meeting. Sydney, 8-13 May 1988. Proceedings of meetings of special societies and colleges. Abstracts., 1988 May, Aust N Z J MedRead more