GTX101105 IP Image
GTX101105 IP Image
Prohibitin antibody
GTX101105
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameProhibitin antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.71 mg/ml
- IsotypeIgG
- Scientific DescriptionProhibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3 untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3 untranslated region may function as a trans-acting regulatory RNA. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- 5-Methoxytryptophan-dependent protection of cardiomyocytes from heart ischemia reperfusion injury. Chou HC et al., 2014 Feb 1, Arch Biochem BiophysRead more
- A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and beta-catenin-ABCG2 signaling. Fang CH et al., 2020 Mar 13, J Biomed SciRead more
- Contribution of Extracellular Matrix and Signal Mechanotransduction to Epithelial Cell Damage in Inflammatory Bowel Disease Patients: A Proteomic Study. Moriggi M et al., 2017 Dec, ProteomicsRead more
- Targeting prohibitins with chemical ligands inhibits KRAS-mediated lung tumours. Yurugi H et al., 2017 Aug 17, OncogeneRead more