Rabbit IgG isotype control (PE)
GTX35037
Overview
- SupplierGeneTex
- Product NameRabbit IgG isotype control (PE)
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.025 mg/ml
- ConjugateRPE
- HostRabbit
- IsotypeIgG
- Scientific DescriptionInclusion of an appropriate isotype control is essential for the proper interpretation of experimental results. Because isotype control antibodies have no relevant specificity, they enable the researcher to distinguish non-specific background binding from antigen-specific antibody binding. Non-specific binding of primary antibodies may occur due to either binding of antibody to Fc receptors or non-specific interactions with cellular proteins, lipids, or carbohydrates. Additionally, autofluorescence or endogenous enzyme activity in target cells may give a false positive that could be misinterpreted as antibody binding. These factors vary by target cell type and the isotype of the primary antibody. Therefore, the primary antibody used should be matched to an isotype control of identical species and isotype (including both heavy and light chains).
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity. Cardo-Vila M et al., 2016 Aug, Am J PatholRead more
- Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens. Karjalainen K et al., 2015 Jul 1, Clin Cancer ResRead more