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GTX114161 ICC/IF Image
GTX114161 ICC/IF Image
GTX114161 ICC/IF Image

Rhotekin antibody

Research Use Only
GTX114161
GeneTex
Product group Antibodies
Price on request
Packing Size
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Overview

  • Supplier
    GeneTex
  • Product Name
    Rhotekin antibody
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Concentration
    0.54 mg/ml
  • Isotype
    IgG
  • Scientific Description
    This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203

References

  • Midbody localization of vinexin recruits rhotekin to facilitate cytokinetic abscission. Chang YW et al., 2017, Cell Cycle
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