Semaphorin-4D Antibody / SEMA4D

Biorbyt

Semaphorin-4D Antibody / SEMA4D

16

Flow Cytometry

Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml FACS, IF

Research Use Only

SEMA4D/933

IgG

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

12352203