SH3RF1 antibody, PAb

Biorbyt

SH3RF1 antibody, PAb

10

Western Blot

WB:1:1000-1:3000 WB

Research Use Only

Polyclonal

100 ug/ml

Unconjugated

Rabbit

IgG

Rabbit polyclonal to SH3RF1. E3 ubiquitin-protein ligase SH3RF1 belongs to the SH3RF family. SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Human, Mouse

2°C to 8°C,-20°C

12352203