GTX83651 WB Image
Shh antibody [10H6] - Overexpression Validated
GTX83651
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityCanine, Human, Monkey, Rat
Overview
- SupplierGeneTex
- Product NameShh antibody [10H6] - Overexpression Validated
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID10H6
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionBinds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction.
- ReactivityCanine, Human, Monkey, Rat
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203