GTX113839 IHC-Fr Image
GTX113839 IHC-Fr Image
SNAP25 antibody
GTX113839
Product group Antibodies
Overview
- SupplierGeneTex
- Product NameSNAP25 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.27 mg/ml
- IsotypeIgG
- Scientific DescriptionSynaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
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- Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice. Xu Y et al., 2020 Jul 23, Aging (Albany NY)Read more
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- Oleocanthal ameliorates amyloid-beta oligomers toxicity on astrocytes and neuronal cells: In vitro studies. Batarseh YS et al., 2017 Jun 3, NeuroscienceRead more
- Plasma Rich in Growth Factors (PRGF) Disrupt the Blood-Brain Barrier Integrity and Elevate Amyloid Pathology in the Brains of 5XFAD Mice. Duong QV et al., 2019 Mar 25, Int J Mol SciRead more
- Preparation of polysomal fractions from mouse brain synaptoneurosomes and analysis of polysomal-bound mRNAs. Kuzniewska B et al., 2018 Jan 1, J Neurosci MethodsRead more