Overview
- SupplierGeneTex
- Product NameSOX2 antibody [GT1352]
- Delivery Days Customer9
- CertificationResearch Use Only
- Clone IDGT1352
- Concentration1 mg/ml
- IsotypeIgG
- Scientific DescriptionThis intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Comprehensive Exploration to Identify Predictive DNA Markers of deltaNp63/SOX2 in Drug Resistance in Human Esophageal Squamous Cell Carcinoma. Ooizumi Y et al., 2019 Dec, Ann Surg OncolRead more
- Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2. Yang SC et al., 2019 Sep, FASEB JRead more
- From ACTH-Dependent to ACTH-Independent Cushings Syndrome from a Malignant Mixed Corticomedullary Adrenal Tumor: Potential Role of Embryonic Stem Cells. Ramirez-Renteria C et al., 2020, Case Rep EndocrinolRead more